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Mae Fah Luang University was established in 1998 and known as the "University in the Park" for its spectacular 800 hectare wooded hillside campus in the northern district of Chiang Rai. It was named after the "Princess Mother" Srinigarindha, whose son Bhumibol was King of Thailand from 1946 to 2016.

It was started with just 64 students but by 2014 it had 12,700, including nearly 1,000 graduates and 450 overseas students, spread across 14 schools including cosmetic science and anti-aging and regenerative medicine, making it the fastest-growing of Thailand¡¯s private universities. Its philosophy is to "restore forests and develop people" and declared has goals of "new, different and better".

All classes except nursing and Thai law are taught in English and there is a single satellite campus in Bangkok, which hosts the school of anti-aging and regenerative medicine.

Located more than 300 miles north of Bangkok in the Greater Mekong Subregion, also sometimes known as the Golden Triangle, it proclaims itself a "centrally located education hub for all six countries" ¨C Thailand, Vietnam, Burma, Cambodia, Laos and China.

The Medical Hub built around the University Hospital established in 2012 offers services across the region.

MFL research in 2017 showed that any benefits from Chinese dam-building projects on the Mekong would be far outweighed by the damage done to fisheries downstream in the other five countries, and in 2019 it launched the "City of Herbs" project in the region, based on traditional local medical practices. Vocational classes run by the university include flight attendant training.